Antileukemic Properties and Structure-Activity Relationships of O- and SGlycosylated Derivatives of Juglone and Related 1,4-Naphthoquinones

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چکیده

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Antileukemic Properties and Structure-Activity Relationships of O- and S- Glycosylated Derivatives of Juglone and Related 1,4-Naphthoquinones

Glycosylated derivatives of physiologically active natural compound juglone and related 1,4naphthoquinones are known as antifungal, immunomodulatory, and antitumor substances. However, their antileukemic properties and structure-activity relationships have been studied insufficiently. Antileukemic effects and structure-activity relationships (SAR) of the 50 1,4naphthoquinone derivatives were ex...

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ژورنال

عنوان ژورنال: Open Glycoscience

سال: 2011

ISSN: 1875-3981

DOI: 10.2174/1875398101104010001